Revenue is to write to around 12,000 people to remind them to include Airbnb income on their tax returns.
The company has provided details of payments made to its customers in 2014, 2015 and 2016 for the provision of short-term accommodation.
In the letter from the tax office, guidance will be provided on the correct tax treatment of the income and on how to correct returns already made, where necessary.
Revenue says the "vast majority of taxpayers are fully compliant with their tax obligations", but added it is "constantly" monitoring new and emerging risks posed by online business.
Revenue will also carry out a range of follow-up compliance checks to ensure that returns are filed and are correct.